Flagellate Dermatitis after Bleomycin / Reply

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Bleomycin-induced flagellate dermatitis

A 29-year-old woman with stage IVB Hodgkin's lymphoma was treated with doxorubicin, bleomycin, vinblastine, and dacarbazine. Two weeks after the first cycle was completed, she developed pruritic, linear erythematous lesions in a flagellate-like pattern on the trunk, neck and arms. After oral prednisone therapy and cessation of bleomycin, the lesions started to recede.

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Bleomycin-Induced Flagellate Dermatitis

Flagellate dermatitis is an uncommon cutaneous drug reaction with a characteristic whip-like appearance that occurs in the setting of bleomycin administration, an agent used in chemotherapy. Bleomycin toxicity is frequently dose-related and lesions typically disappear after discontinuation of the drug although residual hyperpigmentation can remain. Due to the number of patients undergoing treat...

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[Flagellate dermatitis after eating shiitake mushrooms].

test and the episode, the explanation for this phenomenon continues to be a subject of speculation. The tuberculin test may have acted as a traumatic or infectious trigger that activated the patient’s innate immunity, thus increasing TNFproduction by the plasmacytoid dendritic cells and stimulating local activation and proliferation of pathogenic T cells, thereby leading to the episode. Because...

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Bleomycin‐induced flagellate hyperpigmentation

A 27-year old male with Hodgkin's lymphoma was treated with combined chemotherapy that included bleomycin. He presented with pruritic erythematous, edematous linear lesions and was diagnosed to have flagellate hyperpigmentation, a rare side effect of bleomycin chemotherapy.

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Bleomycin-induced flagellate erythema.

of bleomycin or its derivative peplomycin, occurs in 8-20% patients during systemic or local therapy (1). It characterised by a linear erythematous streak with hyperpigmentation (2, 3), and was first described by Moulin in 1970 (4). Herein, we present a typical case of flagellate erythema induced by Bleomycin. A 32 year-old Taiwanese male with mixed germ cell tumour of the anterior mediastinum ...

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ژورنال

عنوان ژورنال: Dermatology

سال: 1990

ISSN: 1018-8665,1421-9832

DOI: 10.1159/000247939